Construction and bioanalytical applications of poly-adenine-mediated gold nanoparticle-based spherical nucleic acids

Author:

Shang Zhiwei1ORCID,Deng Zixuan1,Yi Xiaoqing2ORCID,Yang Mengyu1,Nong Xianliang1,Lin Meihua1ORCID,Xia Fan1ORCID

Affiliation:

1. State Key Laboratory of Biogeology and Environmental Geology, Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China

2. Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou 341000, China

Abstract

This review summarizes the properties and synthesis methods of polyA-mediated SNAs, followed by their applications in biosensing. Discussion and an outlook on future challenges in this field are also presented.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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