Glyoxalase-based toolbox for the enantioselective synthesis of α-hydroxy carboxylic acids

Author:

Yedigenov Mussa1ORCID,Amire Niyaz1,Abdirassil Aizat1ORCID,Mulikova Tomiris1,Begenov Azamat1,Kiesilä Anniina2,Peshkov Anatoly A.1,Peshkov Vsevolod A.12,Utepbergenov Darkhan1ORCID

Affiliation:

1. Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, 53 Kabanbay Batyr Ave, Astana, 010000, Kazakhstan

2. Department of Chemistry, University of Jyväskylä, Survontie 9 B, FI-40014, Finland

Abstract

Glyoxalases DJ-1 and GlxI/II were used for the enantioselective conversion of 13 (hetero)aryl glyoxals to l- and d-α-hydroxy carboxylic acids, respectively.

Funder

Nazarbayev University

Publisher

Royal Society of Chemistry (RSC)

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. cPGA hydrolase assay of DJ-1 in crude cell lysates: Implications for sensing of oxidative stress;Analytical Biochemistry;2024-11

2. Synthetic applications of the Cannizzaro reaction;Beilstein Journal of Organic Chemistry;2024-06-19

3. Hot off the Press;Natural Product Reports;2024

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