Polyacrylic acid coated nanoparticles elicit endothelial cell apoptosis and diminish vascular relaxation in ex vivo perfused iliac arteries of the cane toad (Rhinella marina)-Reference-Cited by-同舟云学术

Polyacrylic acid coated nanoparticles elicit endothelial cell apoptosis and diminish vascular relaxation in ex vivo perfused iliac arteries of the cane toad (Rhinella marina)

Published:2020 Issue:7 Volume:7 Page:1912-1926
ISSN:2051-8153
Container-title:Environmental Science: Nano
language:en
Short-container-title:Environ. Sci.: Nano

Author:

Ortega Van A.¹²³⁴⁵^ORCID,Cameron Melissa S.⁶⁷⁸⁹^ORCID,Stafford James L.¹²³⁴^ORCID,Goss Greg G.¹²³⁴¹⁰^ORCID,Donald John A.¹¹¹²¹³⁹^ORCID,Schultz Aaron G.¹¹¹²¹³⁹^ORCID

Affiliation:

1. Department of Biological Sciences

2. University of Alberta

3. Edmonton

4. Canada

5. Cumming School of Medicine

6. Discipline of Physiology

7. School of Medical Sciences

8. University of Sydney

9. Australia

10. National Institute for Nanotechnology

11. School of Life and Environmental Sciences

12. Deakin University

13. Geelong

Abstract

Cane toad iliac arteries were perfused ex vivo with polyacrylic acid coated nanoparticles. Nanoparticle uptake was observed in both endothelial and vascular smooth muscle cells, eliciting endothelial cell apoptosis and diminished vascular relaxation.

Funder

Company of Biologists

Natural Sciences and Engineering Research Council of Canada

Alberta Innovates - Health Solutions

University of Alberta

Publisher

Royal Society of Chemistry (RSC)

Subject

General Environmental Science,Materials Science (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2020/EN/D0EN00229A

Reference102 articles.