Engineering non-covalently assembled protein nanoparticles for long-acting gouty arthritis therapy-Reference-Cited by-同舟云学术

Engineering non-covalently assembled protein nanoparticles for long-acting gouty arthritis therapy

Published:2021 Issue:48 Volume:9 Page:9923-9931
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhang Jinrui¹²,Sun Yao³,Qu Qian³,Li Bo²,Zhang Lili⁴,Gu Rui¹,Zuo Jianlin¹,Wei Wei⁴,Ma Chao³,Liu Lei³^ORCID,Liu Kai²³^ORCID,Li Jingjing²,Zhang Hongjie²³^ORCID

Affiliation:

1. Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, 130033, China

2. State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

3. Department of Chemistry, Tsinghua University, Beijing, 100084, China

4. Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, Institute of Translational Medicine, Institute of Virology and AIDS Research, The First Hospital of Jilin University, Changchun, Jilin Province 130061, China

Abstract

A new nanoprotein biologic was prepared via noncovalent assembly of an engineered IL-1Ra chimera protein for long-acting gouty arthritis therapy.

Funder

National Natural Science Foundation of China

K. C. Wong Education Foundation

Youth Innovation Promotion Association of the Chinese Academy of Sciences

National Key R&D Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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