Current Challenges and Emerging Therapies in the Treatment of Gout

Author:

Sivaprakasam Shanthini1ORCID,Natarajan Jawahar1ORCID,Singh Jigyasa1ORCID,Rajesh Monisha1ORCID

Affiliation:

1. Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, India

Abstract

Abstract: Gout is a common form of inflammatory arthritis characterized by the deposition of MSU in the joints and surrounding tissues, which results in inflammation and recurrent painful attacks. Currently, xanthine oxidase inhibitors, i.e., Allopurinol and Febuxostat, are used in the therapy. Recently, nanoparticles (NPs) containing metal oxides and non-metal oxides have also been developed to better manage gout. This comprehensive review summarizes the pathophysiology of gout, currently used drugs in the treatment, followed by emerging therapies for gout.

Publisher

Bentham Science Publishers Ltd.

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