Rhodium-catalyzed intramolecular cascade sequence for the formation of fused carbazole-annulated medium-sized rings by cleavage of C(sp2)–H/C(sp3)

Rhodium-catalyzed intramolecular cascade sequence for the formation of fused carbazole-annulated medium-sized rings by cleavage of C(sp2)–H/C(sp3)–H bonds

Published:2018 Issue:66 Volume:54 Page:9147-9150
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Li Qiuyun¹²³⁴⁵,Li Bin¹²³⁴⁵^ORCID,Wang Baiquan¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Elemento-Organic Chemistry

2. College of Chemistry

3. Nankai University

4. Tianjin 300071

5. P. R. China

Abstract

Rhodium(iii)-catalyzed intramolecular annulation of alkyne-tethered 3-(indol-3-yl)-3-oxopropanenitriles for the synthesis of fused carbazole scaffolds via C–H activation has been developed. A series of six-, seven-, and eight-membered hydroazepino[3,2,1-jk]carbazoles were achieved.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Tianjin City

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CC/C8CC04428G

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