Tandem buildup of complexity of aromatic molecules through multiple successive electrophile generation in one pot, controlled by varying the reaction temperature-Reference-Cited by-同舟云学术

Tandem buildup of complexity of aromatic molecules through multiple successive electrophile generation in one pot, controlled by varying the reaction temperature

Published:2016 Issue:5 Volume:14 Page:1680-1693
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Sumita Akinari¹²³⁴,Otani Yuko¹²³⁴,Ohwada Tomohiko¹²³⁴

Affiliation:

1. Graduate School of Pharmaceutical Sciences

2. The University of Tokyo

3. Tokyo 113-0033

4. Japan

Abstract

The unmasking reaction rates and the time of generation of highly reactive electrophiles can be controlled. This reaction system demonstrates the conceptual validity of one-pot build-up of a complex aromatic molecule from multiple starting components.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB02240A

Reference64 articles.

1. A decade of fragment-based drug design: strategic advances and lessons learned

2. Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery

3. A tandem Friedel–Crafts based method for the construction of a tricyclic pyrroloquinoline skeleton and its application in the synthesis of ammosamide B

4. Synthesis of indenes via aluminum chloride-promoted tandem Friedel–Crafts alkylation of arenes and cinnamaldehydes

5. Ytterbium(III) Triflate Catalyzed Tandem Friedel−Crafts Alkylation/Hydroarylation of Propargylic Alcohols with Phenols as an Expedient Route to Indenols

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Superelectrophilic-initiated Friedel–Crafts reaction of diazafluorenols: Synthesis of multi-diazafluorene units (MDAFs);Tetrahedron Letters;2023-11

2. Friedel-Crafts-Type Acylation and Amidation Reactions in Strong Brønsted Acid: Taming Superelectrophiles;Molecules;2022-09-14

3. Copper porphyrin‐catalyzed C(sp 2 ) — O bond construction via coupling phenols with formamides;Journal of the Chinese Chemical Society;2021-04-13

4. Enhancement of the carbamate activation rate enabled syntheses of tetracyclic benzolactams: 8-oxoberbines and their 5- and 7-membered C-ring homologues;Organic & Biomolecular Chemistry;2021

5. Superelectrophiles: Recent Advances;Molecules;2020-07-19