One-pot furan synthesis through diethylzinc-mediated coupling reaction between two α-bromocarbonyl compounds-Reference-Cited by-同舟云学术

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One-pot furan synthesis through diethylzinc-mediated coupling reaction between two α-bromocarbonyl compounds

Published:2023 Issue:42 Volume:21 Page:8463-8466
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hikima Ryo¹,Takeshima Aika¹²,Kano Taichi¹^ORCID

Affiliation:

1. Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan

2. Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan

Abstract

Polysubstituted furans were synthesized in one-pot through the Et2Zn-mediated coupling reaction between dibromoketones and monobromo carbonyl compounds and the subsequent β-elimination with bromoacetyl bromide.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01521A

Reference58 articles.

1. Synthesis of rosefuran. A new route to furans through base-catalyzed cyclization of hydroxy alkynoates and alkynones

2. Developments in Furan Syntheses

3. A.Boto and L.Alvarez , Heterocycles in Natural Product Synthesis , Wiley-VCH Verlag GmbH & Co. KGaA , 2011 , 97

4. Discovery of furan-2-carbohydrazides as orally active glucagon receptor antagonists

5. A review on furan: Formation, analysis, occurrence, carcinogenicity, genotoxicity and reduction methods

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