Promoter engineering of natural product biosynthetic gene clusters in actinomycetes: concepts and applications-Reference-Cited by-同舟云学术

Promoter engineering of natural product biosynthetic gene clusters in actinomycetes: concepts and applications

Published:2024 Issue:4 Volume:41 Page:672-699
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Ji Chang-Hun¹^ORCID,Je Hyun-Woo¹^ORCID,Kim Hiyoung¹,Kang Hahk-Soo¹^ORCID

Affiliation:

1. Department of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Korea

Abstract

Promoter engineering has been used to improve production titers of natural products or to activate transcriptionally silent BGCs. This review summarizes 10 years of progress in promoter engineering approaches in natural products research.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NP/D3NP00049D

Reference157 articles.

1. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

2. The evolving role of natural products in drug discovery

3. Natural Product Total Synthesis: As Exciting as Ever and Here To Stay

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5. Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

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