A new concept for production of (3S,4R)-6-[(benzyloxycarbonyl)amino]-5,6-dideoxyhex-2-ulose, a precursor of d-fagomine-Reference-Cited by-同舟云学术

A new concept for production of (3S,4R)-6-[(benzyloxycarbonyl)amino]-5,6-dideoxyhex-2-ulose, a precursor of d-fagomine

Published:2015 Issue:85 Volume:5 Page:69819-69828
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sudar Martina¹²³⁴,Findrik Zvjezdana¹²³⁴,Vasić-Rački Đurđa¹²³⁴,Soler Anna⁵⁶⁷⁸⁹,Clapés Pere⁵⁶⁷⁸⁹

Affiliation:

1. University of Zagreb

2. Faculty of Chemical Engineering and Technology

3. HR-10000 Zagreb

4. Croatia

5. Institute of Advanced Chemistry of Catalonia

6. Biotransformation and Bioactive Molecules Group

7. IQAC-CSIC

8. 08034 Barcelona

9. Spain

Abstract

A novel cascade reaction combining three enzymes in one pot for the production of aldol adduct (3S,4R)-6-[(benzyloxycarbonyl)amino]-5,6-dideoxyhex-2-ulose was studied and 79% yield on aldol adduct was achieved in the batch reactor.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA14414K

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4. Biotransformation ofD-methionine intoL-methionine in the cascade of four enzymes

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