Cascade enzymatic synthesis of a statin side chain precursor – the role of reaction engineering in process optimization-Reference-Cited by-同舟云学术

Cascade enzymatic synthesis of a statin side chain precursor – the role of reaction engineering in process optimization

Published:2024 Issue:29 Volume:14 Page:21158-21173
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sudar Martina¹^ORCID,Milčić Nevena¹,Česnik Katulić Morana¹,Szekrenyi Anna²,Hernández Karel³,Fekete Melinda⁴⁵,Wardenga Rainer⁴,Majerić Elenkov Maja⁶,Qi Yuyin⁷,Charnock Simon⁷,Vasić-Rački Đurđa¹,Fessner Wolf-Dieter²^ORCID,Clapés Pere³^ORCID,Findrik Blažević Zvjezdana¹

Affiliation:

1. University of Zagreb Faculty of Chemical Engineering and Technology, Savska c. 16, HR-10000 Zagreb, Croatia

2. Technische Universität Darmstadt, Peter-Grünberg-Straße 4, 64287 Darmstadt, Germany

3. Institute of Advanced Chemistry of Catalonia, Biotransformation and Bioactive Molecules Group, IQAC-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain

4. Enzymicals AG, Walther-Rathenau-Straße 49b, 17489 Greifswald, Germany

5. piCHEM Forschungs-und Entwicklungs GmbH, Parkring 3, 8074 Raaba-Grambach, Austria

6. Ruđer Bošković Institute, Bijenička cesta 54, HR-10 000 Zagreb, Croatia

7. Prozomix Ltd, Haltwhistle, Northumberland, NE49 9HA, UK

Abstract

Statins are an important class of drugs used to lower blood cholesterol levels and are often used to combat cardiovascular disease.

Funder

Horizon 2020 Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA01633E

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