Characterization of polysaccharide from longan pulp as the macrophage stimulator

Author:

Yi Yang12345,Wang Hongxun12345,Zhang Ruifen678910,Min Ting1234,Huang Fei678910,Liu Lei678910,Zhang Mingwei678910

Affiliation:

1. College of Food Science & Engineering

2. Wuhan Polytechnic University

3. Wuhan 430023

4. P. R. China

5. Hubei Collaborative Innovation Center for Processing of Agricultural Products

6. Key Laboratory of Functional Food

7. Ministry of Agriculture

8. Sericultural & Agri-food Research Institute

9. Guangdong Academy of Agricultural Sciences

10. Guangzhou 510610

Abstract

A 44.7-kDa polysaccharide LPIIa from longan pulp was mainly composed of →6)-Glc-(1→, →5)-Ara-(1→, →4)-Man-(1→ and →6)-Gal-(1→. It stimulated macrophage activation partlyviaTLR4 and TLR2, followed by p38 MAPK- and NF-κB-dependent signaling pathways.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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