Predicting reactivity for bioorthogonal cycloadditions involving nitrones
Author:
Affiliation:
1. Graduate School of Pharmaceutical Sciences
2. Chiba University
3. Chuo-ku
4. Japan
5. Department of Chemistry and Biomolecular Sciences
6. University of Ottawa
7. Ottawa
8. Canada
Abstract
Nitrones are useful dipoles in both synthesis and in bioorthogonal transformations to report on biological phenomena.
Funder
Natural Sciences and Engineering Research Council of Canada
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA05092J
Reference43 articles.
1. Finding the Right (Bioorthogonal) Chemistry
2. Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
3. Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation
4. Fluorescent labelling in living cells
5. Applications of Bioorthogonal Chemistry in Tumor-Targeted Drug Discovery
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2. Discovery of new tetrazines for bioorthogonal reactions with strained alkenes via computational chemistry;RSC Advances;2024
3. Mechanistic Analysis of Bioorthogonal Double Strain-Promoted Alkyne–Nitrone Cycloadditions Involving Dibenzocyclooctadiyne;ACS Chemical Biology;2023-10-18
4. Bioorthogonal Reactions Utilizing Nitrones as Versatile Dipoles in Cycloaddition Reactions;Chemical Reviews;2021-01-19
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