Discovery of new tetrazines for bioorthogonal reactions with strained alkenes <i>via</i> computational chemistry-Reference-Cited by-同舟云学术

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Discovery of new tetrazines for bioorthogonal reactions with strained alkenes via computational chemistry

Published:2024 Issue:7 Volume:14 Page:4345-4351
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Májek Michal¹^ORCID,Trtúšek Matej¹

Affiliation:

1. Comenius University Bratislava, Faculty of Natural Sciences, Department of Organic Chemistry, Mlynská Dolina, Ilkovičova 6, 842 15 Bratislava, Slovakia

Abstract

Secondary orbital interaction in action: DFT calculations in combination with the distortion–interaction model help to uncover underlying factors responsible for the increased reactivity of sulfone- and sulfoxide-substituted tetrazines in iEDDA.

Funder

Vedecká Grantová Agentúra MŠVVaŠ SR a SAV

HORIZON EUROPE European Research Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA08712C

Reference43 articles.

1. Bioorthogonal chemistry for prodrug activation in vivo

2. Bioorthogonal Chemistry and Its Applications

3. Developing bioorthogonal probes to span a spectrum of reactivities

4. Bioorthogonal chemistry

5. The Future of Bioorthogonal Chemistry

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