Enhanced efficacy in drug-resistant cancer cells through synergistic nanoparticle mediated delivery of cisplatin and decitabine-Reference-Cited by-同舟云学术

Enhanced efficacy in drug-resistant cancer cells through synergistic nanoparticle mediated delivery of cisplatin and decitabine

Published:2020 Issue:3 Volume:2 Page:1177-1186
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Parhizkar M.¹²³⁴⁵^ORCID,Reardon P. J. T.⁶⁷²³⁴,Harker A. H.⁸²³⁴,Browning R. J.⁹¹⁰¹¹¹²⁴,Stride E.⁹¹⁰¹¹¹²⁴^ORCID,Pedley R. B.¹³¹⁴²³⁴,Knowles J. C.⁶⁷²³⁴^ORCID,Edirisinghe M.⁵²³⁴^ORCID

Affiliation:

1. School of Pharmacy

2. University College London

3. London

4. UK

5. Mechanical Engineering

6. Division of Biomaterials and Tissue Engineering

7. UCL Eastman Dental Institute

8. Department of Physics and Astronomy

9. Institute of Biomedical Engineering

10. Department of Engineering Science

11. University of Oxford

12. Oxford

13. UCL Cancer Institute

14. Department of Oncology

Abstract

Co-encapsulation of cisplatin and decitabine in nanoparticles produced by electrohydrodynamic processing. Combination of multiple therapeutic agents in a single nano-carrier could potentially help to overcome drawbacks of monotherapy in cancer treatment.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NA/C9NA00684B

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