A strategy based on isocratic and linear-gradient high-speed counter-current chromatography for the comprehensive separation of platycosides from Platycodi radix-Reference-Cited by-同舟云学术

A strategy based on isocratic and linear-gradient high-speed counter-current chromatography for the comprehensive separation of platycosides from Platycodi radix

Published:2021 Issue:4 Volume:13 Page:477-483
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Yu Jinqian¹²³⁴^ORCID,Chang Xiangwei⁵⁶⁷⁴⁸,Peng Huasheng⁵⁶⁷⁴,Wang Xiao¹²³⁴,Wang Jutao⁵⁶⁷⁴^ORCID,Peng Daiyin⁵⁶⁷⁴,Gui Shuangying⁵⁶⁷⁴⁹

Affiliation:

1. School of Pharmaceutical Sciences

2. Qilu University of Technology (Shandong Academy of Sciences)

3. Jinan

4. China

5. College of Pharmacy

6. Anhui University of Chinese Medicine

7. Hefei

8. Institute of Pharmaceutics

9. Anhui Province Key Laboratory of Pharmaceutical Technology and Application

Abstract

Eight platycosides and three tautomers of acetylated platycosides were isolated from Platycodi radix by an efficient method combined MCI resin column chromatography with isocratic and linear-gradient high-speed counter-current chromatography.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AY/D0AY02029J

Reference20 articles.

1. Committee of the Chinese Pharmacopia , The Chinese Pharmacopia , China Medical Science Press , Beijing , 2020 , vol. 1 , p. 289

2. Antiproliferative Effects of Saponins from the Roots of Platycodon grandiflorum on Cultured Human Tumor Cells

3. Saponins, Especially Platyconic Acid A, from Platycodon grandiflorum Reduce Airway Inflammation in Ovalbumin-Induced Mice and PMA-Exposed A549 Cells