Pyrazinamide-induced hepatotoxicity and gender differences in rats as revealed by a 1H NMR based metabolomics approach-Reference-Cited by-同舟云学术

Pyrazinamide-induced hepatotoxicity and gender differences in rats as revealed by a 1H NMR based metabolomics approach

Published:2017 Issue:1 Volume:6 Page:17-29
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Zhao He¹²³⁴⁵,Si Zhi-Hong⁶⁷⁸⁵,Li Ming-Hui¹²³⁴⁵,Jiang Lei¹²³⁴⁵,Fu Yong-Hong¹²³⁴⁵,Xing Yue-Xiao¹²³⁴⁵,Hong Wei¹²³⁴⁵,Ruan Ling-Yu¹²³⁴⁵,Li Pu-Ming¹²³⁴⁵,Wang Jun-Song¹²³⁴⁵

Affiliation:

1. Center for Molecular Metabolism

2. School of Environmental and Biological Engineering

3. Nanjing University of Science and Technology

4. Nanjing 210094

5. PR China

6. Cancer Hospital

7. Chinese Academy of Sciences

8. Hefei 230031

Abstract

Pyrazinamide disturbed the metabolic profiles of rats with gender difference, with regard to metabolic pathways related to its hepatotoxicity.

Funder

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TX/C6TX00245E

Reference60 articles.

1. A world of cities and the end of TB

2. W. H. Organization , Global tuberculosis control: WHO report 2010, World Health Organization, 2010

3. D. Maher , P.Chaulet, S.Spinaci and A.Harries, Treatment of tuberculosis: guidelines for national programmes, in Treatment of tuberculosis: guidelines for national programmes, 2nd edn, 1997, pp. 1–77

4. Antituberculosis drug-induced hepatotoxicity: Concise up-to-date review

5. LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells

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