Iron-catalyzed hydrogen atom transfer induced cyclization of 1,6-enynes for the synthesis of ketoximes: a combined experimental and computational study-Reference-Cited by-同舟云学术

Iron-catalyzed hydrogen atom transfer induced cyclization of 1,6-enynes for the synthesis of ketoximes: a combined experimental and computational study

Published:2021 Issue:3 Volume:8 Page:643-652
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhao Mingming¹²³⁴⁵,He Wei¹²³⁴⁵,Zou Liang-Hua⁶⁴⁵⁷^ORCID,Wang Dawei¹²³⁴⁵^ORCID,Sun Tian-Yu⁸⁹⁷,Xia Xiao-Feng¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Synthetic and Biological Colloids

2. Ministry of Education

3. School of Chemical and Material Engineering

4. Jiangnan University

5. Wuxi

6. School of Pharmaceutical Sciences

7. China

8. Shenzhen Bay Laboratory

9. Shenzhen

Abstract

An iron-catalyzed reductive radical cyclization/hydro-oximation of 1,6-enynes with tBuONO was developed, leading to functionalized benzofuran, benzothiophene, and cyclopentenyl-based ketoximes.

Funder

National Natural Science Foundation of China

Higher Education Discipline Innovation Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D0QO01341B

Reference83 articles.

1. Ligand‐Promoted Iron(III)‐Catalyzed Hydrofluorination of Alkenes

2. Hydrogen Atom Transfer (HAT)-Triggered Iron-Catalyzed Intra- and Intermolecular Coupling of Alkenes with Hydrazones: Access to Complex Amines