Highly effective and selective FeBr<sub>3</sub>-promoted deuterium bromination/cyclization of 1,<i>n</i>-enynes-Reference-Cited by-同舟云学术

Highly effective and selective FeBr₃-promoted deuterium bromination/cyclization of 1,n-enynes

Published:2024 Issue:5 Volume:22 Page:959-964
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Li Ping¹,Du Zhongjian²,Wu Baofeng³,Zhao Xin³,You Yang'en²^ORCID

Affiliation:

1. Department of Cable Engineering, Henan Institute of Technology, Xinxiang, 453000, China

2. School of Chemistry and Chemical Engineering, Hefei University of Technology and Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, Hefei 230009, China

3. Research Institute of Exploration and Development, PetroChina, Daqing Oilfield Company, Daqing 163712, China

Abstract

A highly effective and selective FeBr3-promoted deuterium bromination/cyclization of 1,n-enynes has been developed, affording heterocyclic alkenyl brominative compounds with good results.

Funder

Science and Technology Department of Henan Province

Natural Science Foundation of Anhui Province

Ministry of Education of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB01778H

Reference77 articles.

1. Applications of Deuterium in Medicinal Chemistry

2. Recent Updates on the Development of Deuterium-Containing Drugs for the Treatment of Cancer

3. Using Deuterium in Drug Discovery: Leaving the Label in the Drug

4. Deuterium in drug discovery: progress, opportunities and challenges

5. Clinical Application and Synthesis Methods of Deuterated Drugs

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