Flexible organic frameworks sequester neuromuscular blocking agents <i>in vitro</i> and reverse neuromuscular block <i>in vivo</i>-Reference-Cited by-同舟云学术

Flexible organic frameworks sequester neuromuscular blocking agents in vitro and reverse neuromuscular block in vivo

Published:2022 Issue:32 Volume:13 Page:9243-9248
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Wu Yan¹^ORCID,Liu Yue-Yang¹^ORCID,Liu Hong-Kun¹,Yu Shang-Bo²^ORCID,Lin Furong²^ORCID,Zhou Wei¹^ORCID,Wang Hui¹,Zhang Dan-Wei¹^ORCID,Li Zhan-Ting¹^ORCID,Ma Da³^ORCID

Affiliation:

1. Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200438, China

2. Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules, Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China

3. School of Pharmaceutical and Materials Engineering & Institute for Advanced Studies, Taizhou University, 1139 Shifu Avenue, Jiaojiang, Zhejiang 318000, China

Abstract

Water-soluble flexible organic frameworks are prepared and used to sequester neuromuscular blocking agents, and reverse their neuromuscular block in vivo.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC02456J

Reference40 articles.

1. Supramolecular hosts as in vivo sequestration agents for pharmaceuticals and toxins

2. Heparin sensing and binding – taking supramolecular chemistry towards clinical applications

3. A Supramolecular Antidote to Macromolecular Toxins Prepared through Coassembly of Macrocyclic Amphiphiles