The synthesis and evaluation of new benzophenone derivatives as tubulin polymerization inhibitors-Reference-Cited by-同舟云学术

The synthesis and evaluation of new benzophenone derivatives as tubulin polymerization inhibitors

Published:2016 Issue:91 Volume:6 Page:88453-88462
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Shun¹²³⁴,An Baijiao¹²³⁴,Yan Jun¹²³⁴,Huang Ling¹²³⁴,Li Xingshu¹²³⁴

Affiliation:

1. School of Pharmaceutical Sciences

2. Sun Yat-sen University

3. Guangzhou

4. China

Abstract

Inspired by the potent inhibition activity of phenstatin and millepachine against cancer cell growth, a series of new benzophenone derivatives were synthesized and evaluated as tubulin polymerization inhibitors.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA16948A

Reference35 articles.

1. Microtubule-stabilizing agents: New drug discovery and cancer therapy

2. Microtubule Targeting Agents: A Benchmark in Cancer Therapy

3. Development of other microtubule-stabilizer families

4. Taxanes, past, present, and future impact on non-small cell lung cancer

5. Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities

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