Site-selective and diastereoselective functionalization of α-amino acid and peptide derivatives via palladium-catalyzed sp3 C

Site-selective and diastereoselective functionalization of α-amino acid and peptide derivatives via palladium-catalyzed sp3 C–H activation

Published:2021 Issue:1 Volume:8 Page:133-168
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhang Ming¹²³⁴⁵^ORCID,Zhong Shengliang¹²³⁴⁵,Peng Yiyuan¹²³⁴⁵^ORCID,Jiang Jianwen¹²³⁴⁵,Zhao Yongli¹²³⁴⁵,Wan Changfeng¹²³⁴⁵,Zhang Zhenming¹²³⁴⁵,Zhang Rongli¹²³⁴⁵,Zhang Ai Qin⁶⁷⁴⁵

Affiliation:

1. College of Chemistry and Chemical Engineering and Key Laboratory of Functional Small Organic Molecules

2. Ministry of Education

3. Jiangxi Normal University (Yaohu campus)

4. Nanchang

5. China

6. Department of Environmental and Chemical Engineering

7. Nanchang Hangkong University

Abstract

This review introduces palladium-catalyzed C–H functionalization of amino acids and peptides.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D0QO00988A

Reference74 articles.

1. Palladium(II)-Catalyzed Enantioselective C(sp3)–H Activation Using a Chiral Hydroxamic Acid Ligand

2. Pyridine-2,6-bis(oxazolines), Helpful Ligands for Asymmetric Catalysts

3. Fluorine-containing amino acids and their derivatives. 4. Synthesis and antibacterial activity of threo and erythro 1-fluorodehydroxylated chloramphenicol analogs

4. Future directions for peptide therapeutics development

5. Therapeutic peptides

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