Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammation
Author:
Affiliation:
1. Laboratory of Food & Health
2. Research Group on Quality
3. Safety and Bioactivity of Plant Foods
4. Department of Food Science and Technology
5. CEBAS-CSIC
Abstract
Urolithin A glucuronide is deconjugated to free urolithin A in systemic inflammation.
Funder
Consejo Superior de Investigaciones Científicas
Ministry of Science, Innovation and Universities
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2019/FO/C9FO00298G
Reference49 articles.
1. Urolithins, the rescue of “old” metabolites to understand a “new” concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status
2. Safety assessment of Urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid
3. The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging
4. Metabolism of Antioxidant and Chemopreventive Ellagitannins from Strawberries, Raspberries, Walnuts, and Oak-Aged Wine in Humans: Identification of Biomarkers and Individual Variability
5. Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far
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