Target-induced structure switching of aptamers facilitates strand displacement for DNAzyme recycling amplification detection of thrombin in human serum-Reference-Cited by-同舟云学术

Target-induced structure switching of aptamers facilitates strand displacement for DNAzyme recycling amplification detection of thrombin in human serum

Published:2019 Issue:7 Volume:144 Page:2430-2435
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Li Jin¹²³⁴,Wang Sujing⁵⁶¹⁷⁸,Jiang Bingying¹²³⁴^ORCID,Xiang Yun⁵⁶¹⁷⁸^ORCID,Yuan Ruo⁵⁶¹⁷⁸

Affiliation:

1. School of Chemistry and Chemical Engineering

2. Chongqing University of Technology

3. Chongqing 400054

4. P. R. China

5. Key Laboratory of Luminescent and Real-Time Analytical Chemistry

6. Ministry of Education

7. Southwest University

8. Chongqing 400715

Abstract

Target-induced sequence proximity leads to strand displacement formation of DNAzymes for amplified detection of thrombin in human serum.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AN/C9AN00030E

Reference46 articles.

1. Sensitive and Homogeneous Protein Detection Based on Target-Triggered Aptamer Hairpin Switch and Nicking Enzyme Assisted Fluorescence Signal Amplification

2. Amplification strategies using electrochemiluminescence biosensors for the detection of DNA, bioactive molecules and cancer biomarkers

3. A simple and sensitive label-free fluorescent approach for protein detection based on a Perylene probe and aptamer

4. An electrochemical aptasensor based on TiO2/MWCNT and a novel synthesized Schiff base nanocomposite for the ultrasensitive detection of thrombin

5. Label-free aptamer biosensor for selective detection of thrombin

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