Diastereoselective synthesis of 3,3-dimethylazetidines via an intramolecular iodine-mediated cyclization reaction

Author:

Jin Hai-Shan1234,Sun Rui1234,Zhou Wei1234,Zhao Li-Ming1234

Affiliation:

1. School of Chemistry and Chemical Engineering, and Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials

2. Jiangsu Normal University

3. Xuzhou 221116

4. China

Abstract

An iodine-mediated intramolecular cyclization reaction of γ-prenylated amines has been developed to provide a convenient route to 3,3-dimethylazetidines.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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2. Substituent and Solvent Effect Studies of N‐Alkenylnitrone 4π Electrocyclizations**;Chemistry – A European Journal;2023-04-17

3. Azetidines, Azetines and Azetes: Monocyclic;Comprehensive Heterocyclic Chemistry IV;2022

4. Advances in synthesis and chemistry of azetidines;Advances in Heterocyclic Chemistry;2020

5. Palladium‐Catalysed Decarboxylative Generation and Regiodivergent Prenylation of 2‐Azaallyl Anions;Advanced Synthesis & Catalysis;2019-07-05

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