Platinum complexes as light promoted anticancer agents: a redefined strategy for controlled activation-Reference-Cited by-同舟云学术

Platinum complexes as light promoted anticancer agents: a redefined strategy for controlled activation

Published:2016 Issue:48 Volume:45 Page:19157-19171
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Mitra Koushambi¹²³⁴

Affiliation:

1. Department of Inorganic and Physical Chemistry

2. Indian Institute of Science

3. Bangalore 560-012

4. India

Abstract

Platinum complexes can act as prodrugs which are non-cytotoxic in the dark but generate active platinum(ii) species and lethal reactive oxygen species on light exposure only in cancer cells, therefore leaving healthy cells unaffected.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/DT/C6DT03665A

Reference130 articles.

1. Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

2. Platinum Compounds: a New Class of Potent Antitumour Agents

3. The resurgence of platinum-based cancer chemotherapy

4. The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

5. Multi-platinum anti-cancer agents. Substitution-inert compounds for tumor selectivity and new targets

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