Switchable synthesis of 1,4-bridged dihydroisoquinoline-3-ones and isoquinoline-1,3,4-triones through radical oxidation of isoquinolinium salts with phenyliodine(<scp>iii</scp>) diacetate-Reference-Cited by-同舟云学术

Switchable synthesis of 1,4-bridged dihydroisoquinoline-3-ones and isoquinoline-1,3,4-triones through radical oxidation of isoquinolinium salts with phenyliodine(iii) diacetate

Published:2022 Issue:17 Volume:9 Page:4676-4684
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Lin Xiao-Long¹,Yu Yan¹,Zhang Liang¹,Leng Li-Jing¹,Xiao Dong-Rong¹^ORCID,Cai Tian¹²,Luo Qun-Li¹²^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China

2. Key Laboratory of Applied Chemistry of Chongqing Municipality, Southwest University, Chongqing 400715, China

Abstract

A switchable synthesis of 1,4-bridged dihydroisoquinoline-3-ones and isoquinoline-1,3,4-triones is developed via radical oxidation of isoquinolinium salts with PhI(OAc)2.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Chongqing

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00887D

Reference45 articles.

1. Total Synthesis of Camptothecin and Related Natural Products by a Flexible Strategy

2. 3-Arylisoquinolines as novel topoisomerase I inhibitors