Synthesis, gallium-68 radiolabelling and biological evaluation of a series of triarylphosphonium-functionalized DO3A chelators-Reference-Cited by-同舟云学术

Synthesis, gallium-68 radiolabelling and biological evaluation of a series of triarylphosphonium-functionalized DO3A chelators

Published:2018 Issue:43 Volume:47 Page:15448-15457
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Smith Adam J.¹²³⁴⁵^ORCID,Gawne Peter J.¹²³⁴⁵^ORCID,Ma Michelle T.⁶⁷⁸⁵^ORCID,Blower Philip J.⁶⁷⁸⁵^ORCID,Southworth Richard⁶⁷⁸⁵^ORCID,Long Nicholas J.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Imperial College London

3. Molecular Sciences Research Hub

4. 80 Wood Lane

5. UK

6. School of Biomedical Engineering and Imaging Sciences

7. King's College London

8. London

Abstract

Gallium-68 chelators with tunable lipophilicities were synthesised, and assessed in both in vitro tumour cells and ex vivo isolated hearts.

Funder

Engineering and Physical Sciences Research Council

Wellcome Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/DT/C8DT02966K

Reference51 articles.

1. Selective targeting of bioactive compounds to mitochondria

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5. The role of mitochondrial membrane potential in ischemic heart failure

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