Di-(2-ethylhexyl) phthalate (DEHP) inhibits steroidogenesis and induces mitochondria-ROS mediated apoptosis in rat ovarian granulosa cells-Reference-Cited by-同舟云学术

Di-(2-ethylhexyl) phthalate (DEHP) inhibits steroidogenesis and induces mitochondria-ROS mediated apoptosis in rat ovarian granulosa cells

Published:2019 Issue:3 Volume:8 Page:381-394
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Tripathi Anima¹²³⁴,Pandey Vivek⁵⁶⁷³⁴,Sahu Alakh N.⁸³⁴,Singh Alok⁹¹⁰³⁴,Dubey Pawan K.⁵⁶⁷³⁴^ORCID

Affiliation:

1. Department of Zoology

2. MMV-BHU

3. Varanasi-221005

4. India

5. Centre for Genetic Disorders

6. Institute of Science

7. Banaras Hindu University

8. Department of Pharmaceutical Eng. & Tech. IIT-BHU

9. Department of Medicine

10. IMS-BHU

Abstract

Increased oxidative stress (OS) due to ubiquitous exposure to di-(2-ethylhexyl) phthalate (DEHP) can affect the quality of oocytes by inducing apoptosis and hampering granulosa cell mediated steroidogenesis.

Funder

Science and Engineering Research Board

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2019/TX/C8TX00263K

Reference49 articles.

1. Estimation of the environmental contamination by phthalic acid esters leaching from household wastes

2. Evaluation of the Direct Toxicity of Trioctyltrimellitate (TOTM), di(2-ethylhexyl) Phthalate (DEHP) and their Hydrolysis Products on Isolated Rat Hepatocytes

3. DEHP-plasticised PVC: relevance to blood services*

4. Diethylhexyl phthalate exposure impairs follicular development and affects oocyte maturation in the mouse

5. Di-(2-ethylhexyl) phthalate and bisphenol A exposure impairs mouse primordial follicle assembly in vitro

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