Integrated analysis of phytochemical composition, pharmacokinetics, and network pharmacology to probe distinctions between the stems of <i>Cistanche deserticola</i> and <i>C. tubulosa</i> based on antidepressant activity-Reference-Cited by-同舟云学术

Integrated analysis of phytochemical composition, pharmacokinetics, and network pharmacology to probe distinctions between the stems of Cistanche deserticola and C. tubulosa based on antidepressant activity

Published:2022 Issue:16 Volume:13 Page:8542-8557
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Fan Li¹,Peng Ying¹,Chen Xiaonan¹,Ma Ping¹,Li Xiaobo¹^ORCID

Affiliation:

1. School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. China

Abstract

The stronger antidepressant activity of CTE over CDE was mainly achieved by 7 bioactive components with higher bioavailability by inhibiting neuronal apoptosis mediated by multiple pathways.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO01357F

Reference36 articles.

1. Human Gastrointestinal Metabolism of the Cistanches Herba Water Extract in Vitro: Elucidation of the Metabolic Profile Based on Comprehensive Metabolite Identification in Gastric Juice, Intestinal Juice, Human Intestinal Bacteria, and Intestinal Microsomes

2. Cistanches Herba: An overview of its chemistry, pharmacology, and pharmacokinetics property

3. A Review of Biologically Active Natural Products from a Desert Plant Cistanche tubulosa