A Ag2CO3/TFA-catalyzed intramolecular annulation approach to imidazo[1,2-c][1,3]oxazin-5-one derivatives-Reference-Cited by-同舟云学术

A Ag₂CO₃/TFA-catalyzed intramolecular annulation approach to imidazo[1,2-c][1,3]oxazin-5-one derivatives

Published:2022 Issue:7 Volume:20 Page:1518-1531
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

El Qami Abdelkarim¹²,Jismy Badr¹,Akssira Mohamed²,Jacquemin Johan¹^ORCID,Tikad Abdellatif³,Abarbri Mohamed¹^ORCID

Affiliation:

1. Laboratoire de Physico-Chimie des Matériaux et des Electrolytes pour l'Energie (PCM2E), EA 6299, Université de Tours, Faculté des Sciences et Techniques, Avenue Monge Faculté des Sciences, Parc de Grandmont, 37200 Tours, France

2. Laboratoire de Chimie Physique et de Chimie Bioorganique, URAC 22. Université Hassan II de Casablanca, Faculté des Sciences et Techniques de Mohammedia, B.P. 146, 28800 Mohammedia, Morocco

3. Laboratoire de Chimie Moléculaire et Substances Naturelles. Université Moulay Ismail, Faculté des Sciences, B.P. 11201, Zitoune, Meknès, Morocco

Abstract

A series of 2,7-disubstituted 3-methylimidazo[1,2-c][1,3]oxazin-5-ones were synthesized in good yields via Ag2CO3/TFA-mediated intramolecular annulation of N-Boc-2-alkynyl-4-bromo(alkynyl)-5-methylimidazoles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D1OB02352G

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