Identification of Novel Antitubulin Agents by Using a Virtual Screening Approach Based on a 7-Point Pharmacophore Model of the Tubulin Colchi-Site-Reference-Cited by-同舟云学术

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Identification of Novel Antitubulin Agents by Using a Virtual Screening Approach Based on a 7-Point Pharmacophore Model of the Tubulin Colchi-Site

Published:2011-10-31 Issue:6 Volume:78 Page:913-922
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:

Author:

Massarotti Alberto,Theeramunkong Sewan,Mesenzani Ornella,Caldarelli Antonio,Genazzani Armando A.,Tron Gian Cesare

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference26 articles.

1. Anticancer therapy with novel tubulin-interacting drugs;Kavallaris;Drug Resist Updat,2001

2. Mechanism of action of antitumor drugs that interact with microtubules and tubulin;Jordan;Curr Med Chem Anticancer Agents,2002

3. The Role of Microtubules in Cell Biology, Neurobiology, and Oncology

4. The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet;van Loo;Cell Death Differ,2002

5. Structure of the tubulin dimer;Luduena;J Biol Chem,1977

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