Continuous-inline extraction of polar co-solvent during sequential flow reactions-Reference-Cited by-同舟云学术

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Continuous-inline extraction of polar co-solvent during sequential flow reactions

Published:2024 Issue: Volume: Page:
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Kobayashi Kwihwan¹^ORCID,Matsuzawa Jun¹,Kawanami Hajime¹^ORCID,Koumura Nagatoshi¹^ORCID

Affiliation:

1. Interdisciplinary Research Center for Catalytic Chemistry, National Institute of Advanced Industrial Science and Technology Central 5, Higashi 1-1-1, Tsukuba, Ibaraki 305-8565, Japan

Abstract

We developed a sequential flow reaction method for aldol condensation and 1,4-conjugate addition using column reactors packed with solid base catalysts.

Funder

New Energy and Industrial Technology Development Organization

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RE/D4RE00276H

Reference41 articles.

1. Seven‐Step Continuous Flow Synthesis of Linezolid Without Intermediate Purification

2. Continuous manufacturing – the Green Chemistry promise?

3. Multigram-scale flow synthesis of the chiral key intermediate of (−)-paroxetine enabled by solvent-free heterogeneous organocatalysis

4. Expedient preparation of active pharmaceutical ingredient ketamine under sustainable continuous flow conditions

5. Development of a multistep reaction cascade for the synthesis of a sacubitril precursor in continuous flow

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