Expedient preparation of active pharmaceutical ingredient ketamine under sustainable continuous flow conditions

Author:

Kassin Victor-Emmanuel H.12345ORCID,Gérardy Romaric12345,Toupy Thomas12345,Collin Diégo12345,Salvadeo Elena12345,Toussaint François12345,Van Hecke Kristof67895ORCID,Monbaliu Jean-Christophe M.12345ORCID

Affiliation:

1. Center for Integrated Technology and Organic Synthesis

2. Research Unit MolSys

3. University of Liège

4. B-4000 Liège (Sart Tilman)

5. Belgium

6. XStruct

7. Department of Chemistry

8. Ghent University

9. B-9000 Ghent

Abstract

Continuous flow preparation of antidepressant ketamine and analogs under sustainable conditions.

Funder

Université de Liège

Fonds De La Recherche Scientifique - FNRS

Universiteit Gent

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference44 articles.

1. Classics in Chemical Neuroscience: Ketamine

2. World Health Organization , WHO Model List of Essential Medicines – 20th List, 2017, http://www.who.int/medicines/publications/essentialmedicines/en/

3. U. S. Drug Enforcement Administration , The Controlled Substances Act, https://www.dea.gov/controlled-substances-act

4. Ketamine blocks bursting in the lateral habenula to rapidly relieve depression

5. World Health Organization , Mental Health, https://www.who.int/mental_health/management/depression/en/

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