High-throughput organ-on-chip platform with integrated programmable fluid flow and real-time sensing for complex tissue models in drug development workflows-Reference-Cited by-同舟云学术

High-throughput organ-on-chip platform with integrated programmable fluid flow and real-time sensing for complex tissue models in drug development workflows

Published:2021 Issue:8 Volume:21 Page:1454-1474
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Azizgolshani H.¹²³,Coppeta J. R.¹²³,Vedula E. M.¹²³,Marr E. E.¹²³,Cain B. P.¹²³,Luu R. J.¹²³,Lech M. P.⁴²³,Kann S. H.¹²³⁵⁶,Mulhern T. J.¹²³,Tandon V.¹²³^ORCID,Tan K.¹²³,Haroutunian N. J.¹²³,Keegan P.¹²³,Rogers M.¹²³,Gard A. L.¹²³,Baldwin K. B.¹²³,de Souza J. C.¹²³,Hoefler B. C.¹²³,Bale S. S.¹²³,Kratchman L. B.¹²³,Zorn A.¹²³,Patterson A.¹²³,Kim E. S.¹²³,Petrie T. A.¹²³,Wiellette E. L.¹²³,Williams C.¹²³,Isenberg B. C.¹²³^ORCID,Charest J. L.¹²³^ORCID

Affiliation:

1. Draper

2. Cambridge

3. USA

4. Pfizer, Inc.

5. Department of Mechanical Engineering

6. Boston University

Abstract

96 microfluidic devices with independent electrical readouts are coupled with 192 micropumps to make a high-throughput organ-on-chip platform.

Funder

Pfizer

National Science Foundation