Copper-catalyzed rapid C–H nitration of 8-aminoquinolines by using sodium nitrite as the nitro source under mild conditions

Author:

Zhu Xiaolei1234,Qiao Li1234,Ye Pingping1234,Ying Beibei1234,Xu Jun1234,Shen Chao5674,Zhang Pengfei1234

Affiliation:

1. College of Material, Chemistry and Chemical Engineering

2. Hangzhou Normal University

3. Hangzhou 310036

4. China

5. College of Biology and Environmental Engineering

6. Zhejiang Shuren University

7. Hangzhou 310015

Abstract

We report the first example of copper(ii) catalyzed remote C–H nitration of 8-aminoquinoline amides by using sodium nitrite as nitration reagent under mild conditions in 1 minute which undergoes single electron process.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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