Synthesis, characterization and evaluation of lecithin-based nanocarriers for the enhanced pharmacological and oral pharmacokinetic profile of amphotericin B-Reference-Cited by-同舟云学术

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Synthesis, characterization and evaluation of lecithin-based nanocarriers for the enhanced pharmacological and oral pharmacokinetic profile of amphotericin B

Published:2015 Issue:42 Volume:3 Page:8359-8365
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Javed Ibrahim¹²³⁴⁵,Hussain Syed Zajif¹²³⁴⁵,Ullah Irfan⁶⁷⁸⁹,Khan Imran¹⁰¹¹¹²¹³¹⁴,Ateeq Muhammad¹⁵¹⁶¹⁷¹⁸⁹,Shahnaz Gul⁶¹⁹²⁰⁹,Rehman Habib ur¹²³⁴⁵,Razi Muhammad Tahir²¹²²²³²⁴⁹,Shah Muhammad Raza¹⁵¹⁶¹⁷¹⁸⁹,Hussain Irshad¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. SBA School of Science & Engineering (SSE)

3. Lahore University of Management Sciences (LUMS)

4. DHA

5. Lahore Cantt 54792

6. Department of Pharmacy

7. University of Peshawar

8. Peshawar - 25120

9. Pakistan

10. Food Science and Biotechnology

11. School of Bioconvergence Science and Technology

12. Kangwon National University

13. Chuncheon

14. Republic of Korea

15. H.E.J. Research Institute of Chemistry

16. International Center for Chemical and Biological Sciences

17. University of Karachi

18. Karachi

19. Quaid-i-Azam University

20. Islamabad 45320

21. Department of Pharmaceutical Chemistry

22. Faculty of Pharmacy

23. Bahauddin Zakariya University

24. Multan 60000

Abstract

Lecithin-drug hybrid nanocarriers (NCs) are demonstrated to enhance oral bioavailability and anti-parasitic potential for poorly water-soluble drugs.

Funder

Higher Education Commission, Pakistan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TB/C5TB01258A

Reference32 articles.

1. Correlates of acute renal failure in patients receiving parenteral amphotericin B

2. Comparison of Amphotericin B with Fluconazole in the Treatment of Acute AIDS-Associated Cryptococcal Meningitis

3. Drug Resistance in Leishmaniasis: Its Implication in Systemic Chemotherapy of Cutaneous and Mucocutaneous Disease

4. Determination of antimony(iii) and total antimony by hydride generation atomic absorption spectrometry in samples of injectable drugs used for leishmaniasis treatment

5. Antileishmanial drug discovery: comprehensive review of the last 10 years

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