Systematic metabolic engineering of Corynebacterium glutamicum for the industrial-level production of optically pure d-(−)-acetoin

Author:

Mao Yufeng123ORCID,Fu Jing123ORCID,Tao Ran123ORCID,Huang Can123ORCID,Wang Zhiwen123ORCID,Tang Ya-Jie45678,Chen Tao12345ORCID,Zhao Xueming123

Affiliation:

1. Key Laboratory of Systems Bioengineering (Ministry of Education); SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin); School of Chemical Engineering and Technology

2. Tianjin University

3. Tianjin, 300072

4. Key Laboratory of Fermentation Engineering (Ministry of Education); Hubei Key Laboratory of Industrial Microbiology

5. Hubei Provincial Cooperative Innovation Center of Industrial Fermentation

6. Hubei University of Technology

7. Wuhan 430068

8. China

Abstract

Acetoin is a high-value-added industrial product and a promising bio-based platform chemical.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference50 articles.

1. Acetoin Metabolism in Bacteria

2. Production of liquid hydrocarbon fuels with acetoin and platform molecules derived from lignocellulose

3. T. Werpy , G.Petersen , A.Aden , J.Bozell , J.Holladay , J.White , A.Manheim , D.Eliot , L.Lasure and S.Jones , Top value added chemicals from biomass. Volume 1-Results of screening for potential candidates from sugars and synthesis gas , Department of Energy , Washington DC , 2004

4. Strategies for enhancing fermentative production of acetoin: A review

5. Efficient acetoin production by optimization of medium components and oxygen supply control using a newly isolatedPaenibacillus polymyxaCS107

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