Diastereoselective synthesis ofcis-1,3-disubstituted isoindolinesviaa highly site-selective tandem cyclization reaction-Reference-Cited by-同舟云学术

Diastereoselective synthesis ofcis-1,3-disubstituted isoindolinesviaa highly site-selective tandem cyclization reaction

Published:2018 Issue:12 Volume:5 Page:1950-1956
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Xing Siyang¹²³⁴⁵^ORCID,Cui Hong¹²³⁴⁵,Qin Jiajing¹²³⁴⁵,Gu Nan¹²³⁴⁵,Zhang Bowei¹²³⁴⁵,Wang Kui¹²³⁴⁵^ORCID,Wang Ying¹²³⁴⁵,Xia Li¹²³⁴⁵,Wang Yumeng¹²³⁴⁵

Affiliation:

1. Tianjin Key Laboratory of Structure and Performance for Functional Molecules; Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry (Tianjin Normal University)

2. Ministry of Education; College of Chemistry

3. Tianjin Normal University

4. Tianjin 300387

5. People's Republic of China

Abstract

A highly site-selective tandem reaction involving regioselective ring opening of aziridines and Michael addition of electron-deficient alkenes has been described.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Tianjin City

Tianjin Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00316E

Reference98 articles.

1. Cascade Reactions Involving Aromatic N-Heterocycles: C-N Bond Formation as Key-step Towards the Synthesis of N-fused Polycyclic Heterocycles