Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve-Reference-Cited by-同舟云学术

Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve

Published:2024 Issue:8 Volume:12 Page:2149-2164
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Melo Sofia F.¹^ORCID,Nondonfaz Alicia¹,Aqil Abdelhafid²,Pierrard Anna²^ORCID,Hulin Alexia¹,Delierneux Céline¹,Ditkowski Bartosz¹,Gustin Maxime¹,Legrand Maxime³,Tullemans Bibian M. E.⁴,Brouns Sanne L. N.⁴,Nchimi Alain¹,Carrus Raoul³,Dejosé Astrid³,Heemskerk Johan W. M.⁴,Kuijpers Marijke J. E.⁴,Ritter Jan⁵,Steinseifer Ulrich⁵,Clauser Johanna C.⁵^ORCID,Jérôme Christine²,Lancellotti Patrizio¹,Oury Cécile¹^ORCID

Affiliation:

1. Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium

2. Center for Education and Research on Macromolecules (CERM), CESAM Research Unit, Department of Chemistry, University of Liège, Allée du 6 août 13, B6a, 4000 Liège, Belgium

3. Sirris, Liège Science Park, Rue du Bois Saint-Jean 12, 4102 Seraing, Belgium

4. Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry, Maastricht University, Universiteitssingel 50, 6200 MD Maastricht, The Netherlands

5. Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty RWTH Aachen University, Pauwelsstraße 20, 52074 Aachen, Germany

Abstract

Non-isocyanate polyurethanes (NIPUs) were developed and tested in vitro. Prosthetic heart valves made of NIPU were designed and manufactured. NIPUs showed low thrombogenicity and the produced valves performed well in terms of hydrodynamics.

Funder

Fonds De La Recherche Scientifique - FNRS

Fonds Léon Fredericq

Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture

Stichting Euregio Maas-Rijn

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D3BM01911J

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