European Society of Cardiology: cardiovascular disease statistics 2021

Author:

Timmis Adam1ORCID,Vardas Panos23,Townsend Nick4ORCID,Torbica Aleksandra5ORCID,Katus Hugo6,De Smedt Delphine7ORCID,Gale Chris P.8ORCID,Maggioni Aldo P.9,Petersen Steffen E.1ORCID,Huculeci Radu3,Kazakiewicz Dzianis3,de Benito Rubio Victor3,Ignatiuk Barbara10,Raisi-Estabragh Zahra1ORCID,Pawlak Agnieszka11,Karagiannidis Efstratios12ORCID,Treskes Roderick13,Gaita Dan14,Beltrame John F.15,McConnachie Alex16ORCID,Bardinet Isabel17,Graham Ian18,Flather Marcus19,Elliott Perry20ORCID,Mossialos Elias A.21ORCID,Weidinger Franz22,Achenbach Stephan23,Mimoza Lezha,Artan Goda,Aurel Demiraj,Chettibi Mohammed,Hammoudi Naima,Vardanyan Katarine,Pepoyan Sergey,Sisakian Hamayak,Scherr Daniel,Siostrzonek Peter,Metzer Bernhard,Mustafayev Isah,Jahangirov Tofig,Rustamova Yasmin,Mitkovskaya Natalya,Shibeka Natalya,Stelmashok Valeriy,De Pauw Michel,Lancellotti Patrizio,Claeys Marc,Kušljugić Zumreta,Džubur Alen,Smajić Elnur,Tokmakova Mariya,Traykov Vassil,Milicic Davor,Pasalic Marijan,Pavasovic Sasa,Christodoulides Theodoros,Papasavvas Ilias,Eftychiou Christos,Linhart Aleš,Táborský Miloš,Hutyra Martin,Sørensen Jacob Thorsted,Andersen Mads Jønsson,Kristensen Steen Dalby,Abdelhamid Magdy,Shokry Khaled,Kampus Priit,Laine Mika,Niemelä Matti,Iung Bernard,Cohen Ariel,Leclercq Christophe,Trapaidze Dali,Etsadashvili Kakhaber,Aladashvili Alexander,Bestehorn Kurt,Baldus Stephan,Zeiher Andreas M.,Kanakakis John,Patrianakos Alexandria,Chrysohoou Christina,Csanádi Zoltán,Becker Dávid,Járai Zoltán,Hrafnkelsdóttir Þórdís Jóna,Maher Vincent,Crowley Jim,Dalton Barbra,Wolak Arik,Assa Eyal Ben,Zafrir Barak,Murrone Adriano,Spaccarotella Carmen,Urbinati Stefano,Salim Berkinbayev,Orazbek Sakhov,Ayan Abdrakhmanov,Bajraktari Gani,Poniku Docor Afrim,Erkin Mirrakhimov,Saamay Abilova,Kurban Kalysov,Erglis Andrejs,Jegere Sanda,Bajare Iveta,Mohammed Malek,Sarkis Antoine,Saadeh Georges,Šlapikas Rimvydas,Lapinskas Tomas,Čelutkienė Jelena,Ellafi Khaled,El Ghamari Fathi,Beissel Jean,Banu Cristiana,Felice Tiziana,Xuereb Robert,Popovici Mihail,Lisii Dorin,Rudi Victor,Boskovic Aneta,Rabrenovic Miroslav,Ztot Samir,Abir-Khalil Saadia,Meeder J.G.,van Rossum A.C.,Elsendoorn M.,Kostov Jorgo,Kostovska Elizabeta Srbinovska,Kedev Sasko,Angel Kristin,Mjølstad Ole Christian,Bleie Øyvind,Gierlotka Marek,Dąbrowski Rafał,Jankowski Piotr,Baptista Sérgio Bravo,Ferreira Jorge,Gil Victor,Badila Elisabeta,Gaita Dan,Popescu Bogdan A.,Shlyakhto Evgeny,Zvartau Nadezhda,Kotova Evgenia,Foscoli Marina,Zavatta Marco,Stojkovic Sinisa,Tesic Milorad,Juricic Stefan,Kaliská Gabriela,Hatala Robert,Hlivák Peter,Fras Zlatko,Bunc Matjaž,Pernat Andrej,Cequier Ángel,Anguita Manuel,Muñiz Javier,Johansson Bengt,Platonov Pyotr,Carballo David,Rüdiger-Stürchler Marjam,Tanner Felix C.,Shebli Hussam Eddin,Kabbani Samer,Abid Leila,Faouzi Addad,Abdessalem Salem,Aytekin Vedat,Atar Ilyas,Kovalenko V.,Nesukay E.,Archbold Andrew,Tayal Upasana,Wilkinson Chris,Kurbanov Ravshanbek,Fozilov Khurshid,Mirmaksudov Mirakhmadjon,Boateng Dennis,Daval Ghislain,Momotyuk Ganna,Sebastiao David,

Affiliation:

1. William Harvey Research Institute, Queen Mary University London, London, UK

2. Hygeia Hospitals Group, HHG, Athens, Greece

3. European Heart Agency, European Society of Cardiology, Brussels, Belgium

4. Department for Health, University of Bath, Bath, UK

5. Centre for Research on Health and Social Care Management (CERGAS), Bocconi University, Milan, Italy

6. Department of Internal Medicine and Cardiology, University of Heidelberg, Heidelberg, Germany

7. Department of Public Health, Ghent University, Ghent, Belgium

8. Medical Research Council Bioinformatics Centre, Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK

9. Research Center of Italian Association of Hospital Cardiologists (ANMCO), Florence, Italy

10. Division of Cardiology, Ospedali Riuniti Padova Sud, Monselice, Italy

11. Mossakowski Medical Research Centre Polish Academy of Sciences, Warsaw, Poland

12. First Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece

13. Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands

14. Universitatea de Medicina si Farmacie Victor Babes, Institutul de Boli Cardiovasculare, Timisoara, Romania

15. University of Adelaide, Central Adelaide Local Health Network, Basil Hetzel Institute, Adelaide, Australia

16. Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK

17. European Society of Cardiology, Sophia Antipolis, France

18. Tallaght University Hospital, Dublin, Ireland

19. Norwich Medical School, University of East Anglia, Norwich, UK

20. Institute of Cardiovascular Science, University College London, London, UK

21. Department of Health Policy, London School of Economics, London, UK

22. Department of Internal Medicine and Cardiology, Klinik Landstrasse, Vienna, Austria

23. Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Abstract

Abstract Aims This report from the European Society of Cardiology (ESC) Atlas Project updates and expands upon the widely cited 2019 report in presenting cardiovascular disease (CVD) statistics for the 57 ESC member countries. Methods and results Statistics pertaining to 2019, or the latest available year, are presented. Data sources include the World Health Organization, the Institute for Health Metrics and Evaluation, the World Bank, and novel ESC sponsored data on human and capital infrastructure and cardiovascular healthcare delivery. New material in this report includes sociodemographic and environmental determinants of CVD, rheumatic heart disease, out-of-hospital cardiac arrest, left-sided valvular heart disease, the advocacy potential of these CVD statistics, and progress towards World Health Organization (WHO) 2025 targets for non-communicable diseases. Salient observations in this report: (i) Females born in ESC member countries in 2018 are expected to live 80.8 years and males 74.8 years. Life expectancy is longer in high income (81.6 years) compared with middle-income (74.2 years) countries. (ii) In 2018, high-income countries spent, on average, four times more on healthcare than middle-income countries. (iii) The median PM2.5 concentrations in 2019 were over twice as high in middle-income ESC member countries compared with high-income countries and exceeded the EU air quality standard in 14 countries, all middle-income. (iv) In 2016, more than one in five adults across the ESC member countries were obese with similar prevalence in high and low-income countries. The prevalence of obesity has more than doubled over the past 35 years. (v) The burden of CVD falls hardest on middle-income ESC member countries where estimated incidence rates are ∼30% higher compared with high-income countries. This is reflected in disability-adjusted life years due to CVD which are nearly four times as high in middle-income compared with high-income countries. (vi) The incidence of calcific aortic valve disease has increased seven-fold during the last 30 years, with age-standardized rates four times as high in high-income compared with middle-income countries. (vii) Although the total number of CVD deaths across all countries far exceeds the number of cancer deaths for both sexes, there are 15 ESC member countries in which cancer accounts for more deaths than CVD in males and five-member countries in which cancer accounts for more deaths than CVD in females. (viii) The under-resourced status of middle-income countries is associated with a severe procedural deficit compared with high-income countries in terms of coronary intervention, ablation procedures, device implantation, and cardiac surgical procedures. Conclusion Risk factors and unhealthy behaviours are potentially reversible, and this provides a huge opportunity to address the health inequalities across ESC member countries that are highlighted in this report. It seems clear, however, that efforts to seize this opportunity are falling short and present evidence suggests that most of the WHO NCD targets for 2025 are unlikely to be met across ESC member countries.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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