Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry-Reference-Cited by-同舟云学术

Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry

Published:2015 Issue:14 Volume:51 Page:2832-2835
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Cagide F.¹²³⁴,Silva T.¹²³⁴,Reis J.¹²³⁴,Gaspar A.¹²³⁴,Borges F.¹²³⁴,Gomes L. R.⁵⁶⁷⁸⁴,Low J. N.⁹¹⁰¹¹¹²

Affiliation:

1. CIQUP/Departamento de Química e Bioquímica Faculdade de Ciências

2. Universidade do Porto

3. 4169-007 Porto

4. Portugal

5. REQUIMTE/FP-ENAS-Faculdade de Ciências de Saúde

6. Escola Superior de Saúde da UFP

7. Universidade Fernando Pessoa

8. P-4200-150 Porto

9. Department of Chemistry

10. University of Aberdeen

11. Old Aberdeen

12. Scotland

Abstract

Discovery of monoamine oxidase-B inhibitors based on chromane-2,4-dione and chromone-3-carboxamide scaffolds for the management of neurodegenerative diseases.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C4CC08798D

Reference16 articles.

1. Parkinson's Disease Management. Part II- Discovery of MAO-B Inhibitors Based on Nitrogen Heterocycles and Analogues

2. Discovery of MAO-B Inhibitors - Present Status and Future Directions Part I: Oxygen Heterocycles and Analogs

3. Monoamine oxidase-B inhibitors in the treatment of Alzheimers disease

4. Chromone: A Valid Scaffold in Medicinal Chemistry

5. Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B

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