I<sub>2</sub>/PPh<sub>3</sub>‐Mediated Cyclization of Enaminones with Sodium Sulfinates: A Protocol for the Synthesis of 3‐Thiolated Chromones-Reference-Cited by-同舟云学术

I₂/PPh₃‐Mediated Cyclization of Enaminones with Sodium Sulfinates: A Protocol for the Synthesis of 3‐Thiolated Chromones

Published:2023-11-10 Issue:12 Volume:12 Page:
ISSN:2193-5807
Container-title:Asian Journal of Organic Chemistry
language:en
Short-container-title:Asian J Org Chem

Author:

Du Jing¹,Zhao Shi‐Yi¹,Hu Zhi‐Chao¹,Dong Zhi‐Bing¹²³^ORCID

Affiliation:

1. School of Chemistry and Environmental Engineering Wuhan Institute of Technology Wuhan 430205 China

2. School of Chemistry and Chemical Engineering Henan Normal University Xinxiang 453007 China

3. Key Laboratory of Green Chemical Process Ministry of Education Wuhan Institute of Technology Wuhan 430205 China

Abstract

AbstractAn I2/PPh3‐mediated synthesis of 3‐thiolated chromones starting from 2‐hydroxyphenylenones and sodium sulfinates was reported. This method features one pot manner, metal‐free, easy performance, readily available starting materials and illustrating potential value for some biologically or pharmaceutically active compounds. In addition, a possible mechanism was proposed based on the control experiments.

Publisher

Wiley

Subject

Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajoc.202300499

Reference75 articles.

2. Synthesis, nematicidal activity and docking study of novel chromone derivatives containing substituted pyrazole

3. Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances

4. Design, syntheses, and antitumor activity of novel chromone and aurone derivatives

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