Ruthenium complexes as prospective inhibitors of metallo-β-lactamases to reverse carbapenem resistance
Author:
Affiliation:
1. Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education
2. College of Chemistry and Materials Science
3. Northwest University
4. Xi'an 710127
5. P. R. China
Abstract
The widespread prevalence of metallo-β-lactamase (MβL)-mediated pathogens has seriously caused a loss of efficacy of carbapenem antibacterials, the last resort for the treatment of severe infectious diseases.
Funder
Natural Science Foundation of Shaanxi Province
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/DT/D0DT02430A
Reference37 articles.
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