Development of a near-infrared ratiometric fluorescent probe for glutathione using an intramolecular charge transfer signaling mechanism and its bioimaging application in living cells
Author:
Affiliation:
1. Key Laboratory of Science and Technology of Eco-Textiles
2. Ministry of Education
3. College of Chemistry, Chemical Engineering and Biotechnology
4. Donghua University
5. Shanghai 201620
Abstract
A novel NIR ratiometric fluorescent probe HBT-GSH was developed for the selective detection of GSH over Cys and Hcy in aqueous solution. The signaling mechanism of the GSH-induced removal of an acetyl group and the switching on of ICT fluorescence was proposed.
Funder
Natural Science Foundation of Shanghai
Dalian University of Technology
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2019/TB/C8TB02864H
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