A nitrilase-mediated entry to 4-carboxymethyl-β-lactams from chemically prepared 4-(cyanomethyl)azetidin-2-ones-Reference-Cited by-同舟云学术

A nitrilase-mediated entry to 4-carboxymethyl-β-lactams from chemically prepared 4-(cyanomethyl)azetidin-2-ones

Published:2016 Issue:59 Volume:6 Page:54573-54579
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Decuyper Lena¹²³⁴⁵,Piens Nicola¹²³⁴⁵,Mincke Jens¹²³⁴⁵,Bomon Jeroen¹²³⁴⁵,De Schrijver Bert¹²³⁴⁵,Mollet Karen¹²³⁴⁵,De Winter Karel⁶³⁴⁵⁷,Desmet Tom⁶³⁴⁵⁷,D'hooghe Matthias¹²³⁴⁵

Affiliation:

1. SynBioC Research Group

2. Department of Sustainable Organic Chemistry and Technology

3. Faculty of Bioscience Engineering

4. Ghent University

5. B-9000 Ghent

6. Department of Biochemical and Microbial Technology

7. Belgium

Abstract

4-(Cyanomethyl)azetidin-2-ones were efficiently prepared from 1,2:5,6-di-O-isopropylidene-d-mannitol, followed by a nitrilase-catalyzed hydrolysis to 4-carboxymethyl β-lactams without affecting the sensitive four-membered ring system.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA08213K

Reference65 articles.

1. Improving known classes of antibiotics: an optimistic approach for the future

2. J. D. C. Yao and R. C.Moellering Jr, Manual of Clinical Microbiology, 9th edn, 2007, vol. 1, pp. 1077–1113

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