Using oxidant susceptibility of thiol stabilized nanoparticles to develop an inflammation triggered drug release system-Reference-Cited by-同舟云学术

Using oxidant susceptibility of thiol stabilized nanoparticles to develop an inflammation triggered drug release system

Published:2015 Issue:8 Volume:3 Page:1597-1604
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Muhammad Faheem¹²³⁴⁵,Qi Wenxiu⁶³⁴⁵,Wang Aifei¹²³⁴⁵,Gu Jingkai⁶³⁴⁵,Du Jianshi⁷³⁴⁵,Zhu Guangshan¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Inorganic Synthesis and Preparative Chemistry

2. College of Chemistry

3. Jilin University

4. Changchun

5. China

6. College of Life Science

7. China Japan Union Hospital

Abstract

Ultrasmall thiol passivated ZnS NPs are prepared using a newly developed synthetic protocol. Exposure to hydroxyl radicals results in oxidation of the thiol groups, thus destabilizing the ZnS nanolids to open drug encompassing pores for attaining an inflammation responsive drug delivery system.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TB/C4TB01709A

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