Stereoselective synthesis of chiral sultam-fused dihydropyridinones <i>via</i> photopromoted NHC catalyzed [4 + 2] annulation-Reference-Cited by-同舟云学术

Stereoselective synthesis of chiral sultam-fused dihydropyridinones via photopromoted NHC catalyzed [4 + 2] annulation

Published:2022 Issue:19 Volume:9 Page:5191-5196
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Chen Yangxu¹,Shi Bai¹,Yin Huiping¹,Liu Yinping¹,Yu Chenxia¹,Zhang Kai¹^ORCID,Li Tuanjie¹,Yao Changsheng¹^ORCID

Affiliation:

1. Jiangsu Key Lab of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, Jiangsu 221116, P R China

Abstract

A photopromoted NHC catalyzed asymmetric [4+2] annulation of saccharine-derived azadienes and α-diazoketones was developed, affording the corresponding sultam-fused dihydropyridinones efficiently (up to 80% yield, 99% ee and >20 : 1 d.r.).

Funder

Natural Science Research of Jiangsu Higher Education Institutions of China

Jiangsu Normal University

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00908K

Reference71 articles.