Induction of cryptic metabolites of the endophytic fungus Trichocladium sp. through OSMAC and co-cultivation

Author:

Tran-Cong Nam Michael1234,Mándi Attila5678ORCID,Kurtán Tibor5678ORCID,Müller Werner E. G.910114ORCID,Kalscheuer Rainer1234,Lin Wenhan12131415ORCID,Liu Zhen1234ORCID,Proksch Peter1234

Affiliation:

1. Institute of Pharmaceutical Biology and Biotechnology

2. Heinrich Heine University Düsseldorf

3. 40225 Düsseldorf

4. Germany

5. Department of Organic Chemistry

6. University of Debrecen

7. H-4002 Debrecen

8. Hungary

9. Institute of Physiological Chemistry

10. Universitätsmedizin der Johannes Gutenberg-Universität Mainz

11. 55128 Mainz

12. State Key Laboratory of Natural and Biomimetic Drugs

13. Peking University

14. Beijing 100191

15. China

Abstract

The endophytic fungus Trichocladium sp. isolated from roots of Houttuynia cordata yielded fifteen compounds including five new ones through OSMAC and co-cultivation approaches.

Funder

European Regional Development Fund

Deutsche Forschungsgemeinschaft

Jürgen Manchot Stiftung

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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