Development of a convenient method for the determination of dimethyl sulfoxide in lyophilised pharmaceuticals by static headspace gas chromatography-mass spectrometry
Author:
Affiliation:
1. Department of Pharmacy – Center for Drug Research
2. Ludwig-Maximilians-University
3. DE-81377 Munich
4. Germany
5. Department of Pharmacy – Pharmaceutical Technology and Biopharmacy
Abstract
A reliable and validated static headspace method for the determination of DMSO in lyophilised products.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/AY/C8AY02574F
Reference11 articles.
1. European Pharmacopoeia, 9.0/0763 Dimethyl sulfoxide , 9th edn, 2018
2. In Silico Approaches to Prediction of Aqueous and DMSO Solubility of Drug-Like Compounds: Trends, Problems and Solutions
3. European Pharmacopoeia, 2.4.24 Identification and control of residual solvents , 9th edn, 2018
4. United States Pharmacopeia, 〈467〉 Residual solvents , 31st edn, 2018
5. Freezing injury from “solution effects” and its prevention by natural or artificial cryoprotection
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